Reproductive biology of the mudskipper Boleophthalmus boddarti in Soc Trang

The mudskipper Boleophthalmus boddarti is an amphibious fish widely distributed in the mudflat regions in Asia, but its reproductive biology was poorly stydied. This study was conducted in the Tran De, Soc Trang, Vietnam, from March 2013 to February 2014, to investigate reproductive parameters of B. boddarti. Data analysis based on a total of 360 collected fish (188 females and 172 males) suggest that the sex ratio of this mudskipper was not significantly different between dry and wet seasons. This fish was a multiple reproducer and spawned in the wet season with a peak spawning in three main months of this season (August to October) as difference stages of oocytes were observed in the ovaries. The male B. boddarti released sperms during the reproductive season since different type of spermatogonia were found in stage V testis sections. This fish reached 11.52 cm total length at first sex maturation and was high fecundity (9,800-33,800 eggs), indicating a possible adaptation of this species to the monsoonal climate. The understanding of the reproductive biology of B. boddarti provides useful knowledge of its reproductive adaptation to the mudflat toward sustainable management in the study region

Indigenous knowledge in climate change adaptation: Case studies of ethnic minorities in the Northern Mountain Region of Vietnam

This study aims to investigate the indigenous knowledge (IK) of three ethnic minority groups in the Northern Mountain Region (NMR) of Vietnam. The groups include (1) Tay people who live at lower elevations; (2) a Dao community who tend to live in the middle elevations and (3) Hmong farmers who mainly reside at higher elevations areas of the mountain. This research intends to identify climate change (CC) and its impact on agricultural cultivation and find out how these groups can adapt to CC by applying their IK in agriculture practices. Data was collected through focus group discussions (n=9), in-depth interviews (n=80), and participant observation. From the 80 respondents, 27 live in Bac Kan province, 23 in Yen Bai province and 30 in Son La province; those who had experience in agricultural production, elderly and village heads. The results show that the NMR weather has significant changes that negatively impact agriculture cultivation and local livelihood. Although the respondents are from different ethnic minorities, these farmers are highly aware of the CC risks, leading into adaptation practices. While the Tay people's major adaptation strategies include the use of a variety of native plants and changing planting calendars, the Dao and Hmong people apply intercropping and local techniques methods in terracing fields using local varieties of livestock. Our findings highlight the importance of using the IK of ethnic minorities in adaptation towards CC. A better targeting about the use of local resources in future national policies and projects is encouraged.Nghiên cứu này nhằm thu thập kiến thức bản địa (IK) của ba nhóm dân tộc thiểu số ở Miền núi phía Bắc (MNPB) của Việt Nam bao gồm (1) dân tộc Tày chủ yếu sống ở vùng thấp; (2) Người Dao có xu hướng sống ở các độ cao trung bình; và (3) người Hmông chủ yếu cư trú ở các khu vực đồi núi cao. Nghiên cứu này nhằm xác định tình hình biến đổi khí hậu (BĐKH) và tác động của nó đối với sản xuất nông nghiệp, đồng thời tìm hiểu cách thức các nhóm dân tộc thiểu số này có thể thích ứng với BĐKH bằng cách áp dụng các kiến thức bản địa của họ vào thực tiễn sản xuất nông nghiệp. Dữ liệu được thu thập thông qua thảo luận nhóm tập trung (n = 9), phỏng vấn sâu (n = 80) và quan sát người tham gia. Trong số 80 người được hỏi, có 27 người sống ở tỉnh Bắc Kạn; 23 người ở tỉnh Yên Bái và 30 người ở tỉnh Sơn La, là những người có kinh nghiệm sản xuất nông nghiệp, người cao tuổi và trưởng thôn. Kết quả cho thấy thời tiết ở khu vực MNPB đã có những thay đổi so với trước gây tác động xấu đến canh tác nông nghiệp và sinh kế của cộng đồng. Mặc dù những người được hỏi từ các dân tộc khác nhau nhưng họ đều nhận thức được sự thay đổi này của thời tiết, do đó họ đã có những thích ứng riêng. Trong khi người Tày sử dụng giống cây trồng địa phương và thay đổi lịch thời vụ thì người Dao và Hmong chọn phương pháp xen canh và áp dụng kỹ thuật bản địa trên đất ruộng bậc thang và sử dụng gióng vật nuôi bản địa. Các phát hiện của chúng tôi giúp hiểu được tầm quan trọng của việc sử dụng IK trong thích ứng với BĐKH của các dân tộc thiểu số, từ đó có thể hướng đến mục tiêu tốt hơn việc sử dụng các nguồn lực địa phương trong các chính sách và dự án quốc gia trong tương lai

The Effect of the Earned Income Tax Credit on Physical and Mental health—Results from the Atlanta Paycheck Plus Experiment

Policy Points: The Paycheck Plus randomized controlled trial tested a fourfold increase in the Earned Income Tax Credit (EITC) for single adults without dependent children r over 3 years in New York and Atlanta. In New York, the intervention improved economic, mental, and physical health outcomes. In Atlanta, it had no economic benefit or impact on physical health r and may have worsened mental health. In Atlanta, tax filing and bonus receipt were lower than in the New York arm of the trial, which may explain the lack of economic benefits. Lower mental health scores in the treatment group were driven by disadvantaged men, and the study sample was in good mental health

COPPER HEXACYANOFERRATE (II): SYNTHESIS, CHARACTERIZATION, AND CESIUM, STRONTIUM ADSORBENT APPLICATION

Low-cost nanoscale copper hexacyanoferrate (CuHF), a good selective adsorbent for cesium (Cs+) removal, was prepared using the chemical co-precipitation method. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDS), and high-resolution transmission electron microscopy (HR-TEM) were conducted to determine the CuHF morphology. Copper hexacyanoferrate, Cu13[Fe(CN)6]14.(2K).10H2O, has a cubic structure (space group F-43m) in the range of 10-30 nm and a Brunauer-Emmett-Teller (BET) surface area of 462.42 m2/g. The removal of Cs+ and Sr2+ is dependent on pH; the maximum adsorption capacity (qmax) of CuHF is achieved at a pH = 6. From the Langmuir model, qmax = 143.95 mg/g for Cs+ and 79.26 mg/g for Sr2+, respectively. At high concentrations, Na+, Ca2+, and K+ ions have very little effect on Cs+ removal, and Na+ and K+ ions have a higher affinity for removing Sr2+ than Ca2+ at all concentrations. CuHF has a high affinity for alkaline cations in the order: Cs+ > K+ > Na+ > Ca2+ > Sr2+, as proposed and discussed

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke

Good Night?: Clustering Sleep Stage Data

We developed methods to make meaningful clusters of Fitbit sleep data to capture variation in nights’ sleep. Existing dissimilarity measures do not account for the ordering, the timing, and the duration of sleep in successive states, so we propose period-dependent distances between probability distributions adapted for the cyclic nature of sleep. These methods provide unique information about sleep stage data not captured with common sleep summaries and different periods of the night provide unique information about a night’s sleep

Supply chain social responsibility in labour- intensive industries: a practitioner’s perspective

Social responsibility in labour-intensive industries of developing countries is always acontroversial issue among academics and practitioners. Although several studies haveconceptualised or empirically examined social responsibility in developing countries, there islimited research that investigates social responsibility issues spanning the entire manufacturingsupply chain. Using stakeholder and Resource-Based View (RBV) theory, this study examines thebarriers, enablers, motivations, and the current social responsibility facts of the garment and textileindustry from knitting suppliers to apparel or garment manufacturer to fashion retailers in theVietnamese context. The exploratory research design was used through content analysis, paneldiscussion, and in-depth interview. Our results show that most of the companies have notimplemented any significant policies to promote social responsibility but only to adhere to labourlaw. Since managers realize the crucial social responsibility role in the performance of theiroperation, merchandisers and intermediaries have a compelling role in improving their socialresponsibility, and the role of government and NGOs seems to be faded. We also provide themanagerial implications and directions for future research

Regulation of NF-κB- and STAT1-mediated plasmacytoid dendritic cell functions by A20.

Dendritic cells (DCs) are professional antigen presenting cells involved in the induction of T cell-mediated adaptive immunity. Plasmacytoid DCs (pDCs) originate from lymphoid precursors and produce type I interferons (IFNs) in response to pathogens. A20 is considered as a negative regulator of toll-like receptor (TLR) signaling pathways, in which Toxoplasma gondii- derived profilin (TgPRF) is a TLR11/12 ligand recognised by DCs to stimulate their maturation/activation. Little is known about contributions of A20 to changes in biological properties of pDCs. The present study, therefore, explored whether pDC functions are influenced by A20. To this end, bone marrow cells were isolated and cultured with Flt3L to attain CD8DCs, CD11bDCs and pDCs and followed by challenge with TgPRP in the presence or absence of A20 siRNA. Expression of maturation markers were analysed by flow cytometry, and secretion of inflammatory cytokines by ELISA, cell migration by a transwell migration assay and expression of signalling molecules by western blotting. As a result, treatment with A20 siRNA enhanced activations of IκB-α and STAT-1, leading to increases in expressions of maturation markers and cytokine productions as well as migration of TgPRP-treated pDCs, while mature CD11bDCs produced at higher levels of TNF-α and IL-6 only. In addition, functions of CD8DCs remained unaltered following A20 silencing. The effects of A20 on pDC maturation and activation were completely abolished by IKK inhibitor and partially blunted by fludarabine. In conclusion, the inhibitory effects of A20 on pDC functions are expected to affect the immune response in T. gondii infection